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SWISHER, STEPHEN G

One or more keywords matched the following items that are connected to SWISHER, STEPHEN G

Item Type	Name
Academic Article	Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53.
Concept	Cytoskeletal Proteins
Concept	Mitogen-Activated Protein Kinase 8
Concept	Retinoblastoma-Binding Protein 1
Concept	Protein-Tyrosine Kinases
Concept	Membrane Proteins
Concept	Protein Binding
Concept	Protein Phosphatase 1
Concept	DNA-Binding Proteins
Concept	Protein Folding
Concept	Glutathione Reductase
Concept	Heat-Shock Proteins
Concept	Unfolded Protein Response
Concept	Tumor Suppressor Protein p53
Concept	p38 Mitogen-Activated Protein Kinases
Concept	CDC2 Protein Kinase
Concept	Proto-Oncogene Proteins B-raf
Concept	Protein Biosynthesis
Concept	Mitogen-Activated Protein Kinase 9
Concept	Protein Kinase Inhibitors
Concept	Protein Phosphatase 2
Concept	Carrier Proteins
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Cell Cycle Proteins
Concept	Mitogen-Activated Protein Kinase 1
Concept	Insulin-Like Growth Factor Binding Protein 2
Concept	Receptor Protein-Tyrosine Kinases
Concept	Hedgehog Proteins
Concept	Retinoblastoma Protein
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	bcl-2-Associated X Protein
Concept	Neoplasm Proteins
Concept	Insulin-Like Growth Factor Binding Proteins
Concept	JNK Mitogen-Activated Protein Kinases
Concept	Proto-Oncogene Proteins p21(ras)
Concept	Focal Adhesion Protein-Tyrosine Kinases
Concept	bcl-X Protein
Concept	AMP-Activated Protein Kinases
Concept	Intracellular Signaling Peptides and Proteins
Concept	Mitogen-Activated Protein Kinase 3
Concept	Proto-Oncogene Proteins c-met
Concept	Cation Transport Proteins
Concept	Proto-Oncogene Proteins
Concept	bcl-2 Homologous Antagonist-Killer Protein
Concept	Nerve Tissue Proteins
Concept	Tumor Suppressor Proteins
Concept	Protein Array Analysis
Concept	Intercellular Signaling Peptides and Proteins
Concept	Proto-Oncogene Proteins c-kit
Concept	Cornified Envelope Proline-Rich Proteins
Concept	Proto-Oncogene Proteins c-akt
Concept	Proteins
Concept	Thioredoxin-Disulfide Reductase
Academic Article	MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus.
Academic Article	Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.
Academic Article	EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma.
Academic Article	A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax.
Academic Article	Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines.
Academic Article	Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.
Academic Article	Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis.
Academic Article	Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR.
Academic Article	Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer.
Academic Article	Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
Academic Article	JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase.
Academic Article	Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinoma.
Academic Article	Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity.
Academic Article	Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53).
Academic Article	Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores.
Academic Article	Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.
Academic Article	Clinical implications of p53 tumor suppressor gene mutation and protein expression in esophageal adenocarcinomas: results of a ten-year prospective study.
Academic Article	Induction of apoptosis in human lung cancer cells following treatment with amifostine and an adenoviral vector containing wild-type p53.
Academic Article	Enhancement of adenoviral MDA-7-mediated cell killing in human lung cancer cells by geldanamycin and its 17-allyl- amino-17-demethoxy analogue.
Academic Article	Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma.
Academic Article	Development of Ad-mda7/IL-24-resistant lung cancer cell lines.
Academic Article	"Seedling" mesenchymal tumors (gastrointestinal stromal tumors and leiomyomas) are common incidental tumors of the esophagogastric junction.
Academic Article	Absence of pRb facilitates E2F1-induced apoptosis in breast cancer cells.
Academic Article	Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters.
Academic Article	Adenoviral Bak overexpression mediates caspase-dependent tumor killing.
Academic Article	Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells.
Academic Article	Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis.
Academic Article	Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.
Academic Article	The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.
Academic Article	Combination therapy of Ad-mda7 and trastuzumab increases cell death in Her-2/neu-overexpressing breast cancer cells.
Academic Article	Role for the double-stranded RNA-activated protein kinase PKR in Ad-TNF-alpha gene therapy in esophageal cancer.
Academic Article	Gene therapy with E2F-1 up-regulates the protein kinase PKR and inhibits growth of leiomyosarcoma in vivo.
Academic Article	mda-7 gene transfer sensitizes breast carcinoma cells to chemotherapy, biologic therapies and radiotherapy: correlation with expression of bcl-2 family members.
Academic Article	The double-stranded RNA-activated protein kinase mediates radiation resistance in mouse embryo fibroblasts through nuclear factor kappaB and Akt activation.
Academic Article	Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound.
Academic Article	Prognostic significance of combinations of RNA-dependent protein kinase and EphA2 biomarkers for NSCLC.
Academic Article	Insulin-like growth factor binding proteins increase intracellular calcium levels in two different cell lines.
Academic Article	Thymoma patients treated in a phase I clinic at MD Anderson Cancer Center: responses to mTOR inhibitors and molecular analyses.
Academic Article	IGFBP2/FAK pathway is causally associated with dasatinib resistance in non-small cell lung cancer cells.
Academic Article	Prediction of survival in resected non-small cell lung cancer using a protein expression-based risk model: implications for personalized chemoprevention and therapy.
Academic Article	Membrane carbonic anhydrase IX expression and relapse risk in resected stage I-II non-small-cell lung cancer.
Academic Article	Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines.
Academic Article	Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR).
Academic Article	The mitochondrial apoptosis-inducing factor plays a role in E2F-1-induced apoptosis in human colon cancer cells.
Academic Article	Prognostic significance of RNA-dependent protein kinase on non-small cell lung cancer patients.
Academic Article	Synergistic tumoricidal effect between celecoxib and adenoviral-mediated delivery of mda-7 in human breast cancer cells.
Academic Article	Insulin-like growth factor binding protein-2 level is increased in blood of lung cancer patients and associated with poor survival.
Academic Article	Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer.
Academic Article	RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer.
Academic Article	Predictive biomarkers in precision medicine and drug development against lung cancer.
Academic Article	Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity
Academic Article	RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer
Academic Article	Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance
Academic Article	RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer.
Academic Article	Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells.
Academic Article	Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance.
Academic Article	Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients.
Academic Article	HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells.
Academic Article	Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations.
Academic Article	Local Consolidation Therapy (LCT) After First Line Tyrosine Kinase Inhibitor (TKI) for Patients With EGFR Mutant Metastatic Non-small-cell Lung Cancer (NSCLC).
Academic Article	Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis.
Academic Article	Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC.
Academic Article	Validation of the 12-gene Predictive Signature for Adjuvant Chemotherapy Response in Lung Cancer.
Concept	Enhancer of Zeste Homolog 2 Protein
Concept	Zinc Finger Protein GLI1
Concept	Kelch-Like ECH-Associated Protein 1
Concept	Tumor Protein p73
Concept	X-ray Repair Cross Complementing Protein 1
Concept	Coxsackie and Adenovirus Receptor-Like Membrane Protein
Academic Article	Glutathione reductase (GSR) gene deletion and chromosome 8 aneuploidy in primary lung cancers detected by fluorescence in situ hybridization.
Academic Article	Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
Academic Article	High mutational concordance between primary colorectal tumors and associated pulmonary metastases.
Academic Article	Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment.
Academic Article	STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition.
Academic Article	Association of Driver Oncogene Variations With Outcomes in Patients With Locally Advanced Non-Small Cell Lung Cancer Treated With Chemoradiation and Consolidative Durvalumab.
Academic Article	Benchmarking Outcomes for Molecularly Characterized Synchronous Oligometastatic Non-Small-Cell Lung Cancer Reveals EGFR Mutations to Be Associated With Longer Overall Survival.
Academic Article	Lung surveillance following colorectal cancer pulmonary metastasectomy: Utilization of clinicopathologic risk factors to guide strategy.
Academic Article	Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases.

Search Criteria

Protein
Disulfide
Reductase Glutathione